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EATING DISORDERS

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Title:Transcranial magnetic stimulation for comorbid depression in anorexia.
Date:September 2008
Author(s):Kamolz S, Richter MM, Schmidtke A, Fallgatter AJ
Source:Klinik und Poliklinik für Psychiatrie, Psychosomatik und Psychotherapie, Klinikum der Bayerischen Julius-Maximilians-Universität Würzburg, Füchslein Str. 15, 97080, Würzburg, Deutschland.
Abstract:A 24-year-old anorexic patient with cormobid symptoms of depression was treated for depression with repetitive transcranial magnetic stimulation (rTMS) rather than with psychopharmacotherapy, due to her poor physical condition. The depressive symptomatology significantly improved in correlation with two rTMS cycles but occurred again within 2 weeks. A third successful cycle was then followed by a maintenance rTMS protocol with the patient going into remission from depression. This case illustrates that rTMS may be considered as a therapeutic option for comorbid depression in anorectic patients.


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Title:Repetitive transcranial magnetic stimulation: a possible novel therapeutic approach to eating disorders.
Author(s):Tsai SJ.
Source:Med Hypotheses. 2005;65(6):1176-8. Epub 2005 Jul 7.
Abstract:The two most common eating disorders, anorexia nervosa and bulimia nervosa, are characterized by aberrant eating patterns and disturbances in body image. Treatment involves combining individual, behavioural, group, and family therapies, possibly with medications. Studies have found that medication, chiefly antidepressants, could be of help in bulimia nervosa but the evidence is weaker for use in anorexia nervosa. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive technique that briefly stimulates or depresses cortical areas within the brain. It has been used in the treatment of various psychiatric disorders, especially major depression, which is a condition that patients with eating disorders often experience as a significant comorbidity. Given that both disorders may share a common pathogenesis, this report proposes that rTMS may represent an alternative strategy for the treatment of eating disorders. Other evidence that supports this notion comes from animal studies that show that rTMS can change feeding behaviours and central neurotransmitters related to the regulation of eating behaviours. Further investigation into the dose, duration and type of rTMS stimulus is needed to verify the efficacy of this intervention in eating disorders.


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